The ACT Center participates in research of all kinds. Resources available through the ACT Center’s data repository and University of Mississippi Medical Center provides abundant opportunities for research. Please reach out to Jonathan Hontzas at jhontzas@umc.edu or 601-815-1412 with any potential opportunities.
2024
2023
2021
- The Influence of Friends on Teen Vaping: A Mixed-Methods Approach.
- Association between Electronic Nicotine Delivery Systems (ENDS) device and E-liquid alterations and flavor use with clinical and EVALI-like symptoms.
- Determinants of Perceived Factors Discouraging Electronic Nicotine Delivery Systems (ENDS) Use Among Youth and Young Adults.
- Psychological correlates of smoker’s identity in adults reporting mental health diagnoses.
- Tobacco use prevalence and transitions from 2013 to 2018 among adults with a history of cardiovascular disease.
- The emerging global tobacco treatment workforce: Characteristics of Tobacco Treatment Specialists trained in Council-accredited training programs from 2017 to 2019.
- Genome-wide DNA methylation analysis reveals significant impact of long-term ambient air pollution exposure on biological functions related to mitochondria and immune response.
2020
- Gene‐based association analysis reveals involvement of LAMA5 and cell adhesion pathways in nicotine dependence in African‐ and European‐American samples
- Correlates of youth vaping flavor preferences.
- Associations between tobacco use patterns and demographic characteristics of sexual minority and heterosexual youth: Results from a nationwide survey.
- Identification of 34 genes conferring genetic and pharmacological risk for the comorbidity of schizophrenia and smoking behaviors.
- Perceptions of electronic cigarettes among ethno-culturally diverse Latino adults in four US urban centers.
- Tobacco perceptions and practices: User groups and demographic characteristics, Mississippi, USA.
- Socioeconomic and demographic status and perceived health risks of e-cigarette product contents among youth: Results from a national survey.
- Prediction of smoking behavior from single-nucleotide polymorphisms with machine learning approaches.
- Determination of shared genetic etiology and possible causal relations between tobacco smoking and depression.
2019
- Is there a role for electronic cigarettes in tobacco cessation?
- An exome-wide association study identifies new susceptibility loci for age of smoking initiation in African- and European-American populations.
- The role of flavors in vaping initiation and satisfaction among U.S. adults.
- Genetic and epigenetic analysis revealing variants in the NCAM1–TTC12–ANKK1–DRD2 cluster associated significantly with nicotine dependence in Chinese Han smokers.
- Perceived health risks of electronic nicotine delivery systems (ENDS) users: The role of cigarette smoking status.
- Enrollee characteristics in an intensive tobacco dependence treatment program: The relationship of race and sex to demographic factors and tobacco use patterns.
- Cigarette smoking, ENDS use and dual-use among a national sample of lesbians, gays and bisexuals.
- Age differences in electronic nicotine delivery systems (ENDS): Usage motivations and behaviors, perceived health benefit, and intention to quit.
2018
- The social patterning of electronic nicotine delivery system use among US adults.
- Association and cis-mQTL analysis of variants in serotonergic genes associated with nicotine dependence in Chinese Han smokers.
- The ‘state’ of tobacco: Perceptions of tobacco among Appalachian youth in Kentucky.
- Electronic cigarette use prevalence, associated factors, and pattern by cigarette smoking status in the United States from NHANES (National Health and Nutrition Examination Survey) 2013–2014.
- Association and cis-mQTL analysis of variants in CHRNA3-A5, CHRNA7, CHRNB2, and CHRNB4 in relation to nicotine dependence in a Chinese Han population.
- Establishing consensus on survey measures for electronic nicotine and non-nicotine delivery system use: Current challenges and considerations for researchers.
- Detection of significant association between variants in cannabinoid receptor 1 gene (CNR1) and personality in African-American population.
2017
- Relationship between personality traits and nicotine dependence in male and female smokers of African- and European-American samples.
- Establishing consensus on survey measures for electronic nicotine and non-nicotine delivery system use: Current challenges and considerations for researchers.
- Significant association of the CHRNB3-CHRNA6 gene cluster with nicotine dependence in the Chinese Han population.
- Prevalence of cigarette smoking and nicotine dependence in men and women residing in two provinces in China.
2016
- Psychosocial factors are associated with blood pressure progression among African Americans in the Jackson Heart Study.
- Cigarette smoking and chronic kidney disease in African Americans in the Jackson Heart Study.
2015
- The contribution of rare and common variants in 30 genes to risk nicotine dependence.
- Hispanic/Latino knowledge, attitudes, and behaviors about tobacco use: Results of focus groups in four U.S. cities.
- Increasing the Quality and availability of evidence-based treatment for tobacco dependence through unified certification of tobacco treatment specialists.
- Perceived discrimination is associated with health behaviors among African Americans in the Jackson Heart Study.
- Ethnic-specific genetic association of variants in the corticotropin-releasing hormone receptor 1 gene with nicotine dependence.
- The contribution of rare and common variants in 30 genes to risk nicotine dependence.
2014
- The impact of brief tobacco treatment training on practice behaviors, self-efficacy, and attitudes among healthcare providers.
- Introduction to deep sequencing and its application to drug addiction research with a focus on rare variants.
- Significant associations of CHRNA2 and CHRNA6 with nicotine dependence in European American and African American populations.
2013
- Significant association of CHRNB3 variants with nicotine dependence in multiple ethnic populations.
- Depressive symptoms among heavy cigarette smokers: The influence of daily rate, gender, and race.
- Serotonin transporter and receptor genes significantly impact nicotine dependence through genetic interactions in both European American and African American smokers.
2012
- Smoking and genetic risk variation across populations of European, Asian, and African American ancestry ? a meta-analysis of chromosome 15q25.
- Evaluation of the Brief Wisconsin Inventory of Smoking Dependence Motives in African-American and European-American heavy smokers.
- Psychometric Evaluation of the Interpersonal Support Evaluation List ? Short Form (ISEL-SF) in the ARIC Study Cohort.
- National Ambulatory Medical Care Survey (NAMCS): Tobacco intervention practices in outpatient clinics.
- Large-scale genome-wide association study of Asian population reveals genetic factors in FRMD4A and other loci influencing smoking initiation and nicotine dependence.
- Tobacco dependence treatment: Influence of training experiences on clinical activities among otolaryngologists.
2011
2010
- Tobacco cessation via public dental clinics: Results of a randomized trial.
- Do faxed quitline referrals add value to dental office-based tobacco cessation interventions?
- Associations of variants in CHRNA5/A3/B4 gene cluster with smoking behaviors in a Korean population. PLoS Genetics, 6, e12183.
- Significant association of glutamate receptor, ionotropic N-methyl-D-aspartate 3A (GRIN3A), with nicotine dependence in European- and African-American smokers.
- Convergent evidence that choline acetyltransferase gene variation is associated with prospective smoking cessation and nicotine dependence.
- Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.
- Replication and extension of association of choline acetyltransferase with nicotine dependence in European and African American smokers.
- Determination of methylated CpG sites in the promoter region of catechol-O-methyltransferase (COMT) and their involvement in the etiology of tobacco smoking.
2009
- SigniWcant association of glutamate receptor, ionotropic N-methyl-D-aspartate 3A (GRIN3A), with nicotine dependence in European- and African-American smokers.
- Association and interaction analyses of GABBR1 and GABBR2 with nicotine dependence in European- and African-American populations.
- Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans.
- Genome-wide association analyses suggested a novel mechanism for smoking behavior regulated by IL15.
- Treatment for tobacco dependence for rural, lower-income smokers: Outcomes, predictors, and measurement considerations.
- Detection of genetic association and a functional polymorphism of Dynamin 1 gene with nicotine dependence in European and African Americans.
2008
- Significant association of ANKK1 and detection of a functional polymorphism with nicotine dependence in an African American sample.
- Treatment for tobacco dependence for rural, lower-income smokers: Outcomes, predictors, and measurement considerations.
- Detection of genetic association and a functional polymorphism of Dynamin 1 gene with nicotine dependence in European and African Americans.
- A survey of the tobacco-related knowledge, attitudes, and behaviors of primary care providers in Mississippi.
- Association of amyloid precursor protein-binding protein, family B, member 1 with nicotine dependence in African and European American smokers.
- A survey of oral and maxillofacial surgeons' tobacco-use related knowledge, attitudes and intervention behaviors.
- Significant association of DRD1 with nicotine dependence.
- A functional polymorphism, rs6280, in DRD3 is significantly associated with nicotine dependence in European-American smokers.
- Genome-wide linkage scan for nicotine dependence in European Americans and its converging results with African Americans in the Mid-South Tobacco Family sample.
- Bitter taste receptor gene polymorphisms are an important factor in the development of nicotine dependence in African Americans.
- Significant association of the neurexin 1 gene (NRXN1) with nicotine dependence in European and African American smokers.
- ?-arrestins 1 and 2 are associated with nicotine dependence in European-American smokers.
2007
- Psychometric evaluation of a Coping Strategies Inventory short-form (CSI-SF) in the Jackson Heart Study Cohort.
- The 5 A's vs. 3 A's plus proactive quit line referral in private practice dental offices: Preliminary results.
- Serving the public good: Challenges of Dental Education in the 21st Century.
- Linkage and association studies in African- and Caucasian-American populations demonstrate that SHC3 is a novel susceptibility locus for nicotine dependence.
- Fine mapping of a linkage region on chromosome 17p13 reveals that GABARAP and DLG4 are associated with vulnerability to nicotine dependence in European-Americans.
2006
- Association of specific haplotypes of neurotrophic tyrosine kinase receptor 2 gene (NTRK2) with vulnerability to nicotine dependence in African-Americans and European-Americans.
- Significant association of catechol-O-methyltransferase (COMT) haplotypes with nicotine dependence in male and female smokers of two ethnic populations.
- Does the impact of smoking on coronary heart disease differ by low density lipoprotein cholesterol level? The Atherosclerosis Risk in Communities (ARIC) Study.
- A genomewide search finds major susceptibility loci for nicotine dependence on chromosome 10 in African-Americans.
- Linkage and association studies in African- and Caucasian-American populations demonstrate that SHC3 is a novel susceptibility locus for nicotine dependence.
- Gene-based analysis suggests association of the nicotinic acetylcholine receptor _1 subunit (CHRNB1) and M1 muscarinic acetylcholine receptor (CHRM1) with vulnerability for nicotine dependence.
2005
- Single and multi-locus allelic variants within the GABAB receptor subunit 2 (GABAB2) gene are significantly associated with nicotine dependence.
- Significant association of BDNF haplotypes in European American smokers but not in European American female or African American smokers.
- Ethnic- and gender-specific association of the nicotinic acetylcholine receptor a4 subunit gene (CHRNA4) with nicotine dependence.
- Haplotype analysis indicates an association between the DOPA decarboxylase (DDC) gene and nicotine dependence.
- Sociocultural methods in the Jackson Heart Study: Conceptual and descriptive overview.
2003
- A genome wide scan to identify loci for smoking quantity in the Framingham Heart Study population.
- Tobacco update 2002: Scientific advances, clinical perspectives.
- Treating nicotine dependence.
- Characteristics of African-American smokers: A brief review.
- Smoking cessation research in primary care treatment centers: The SCRIPT-MS Project.
2000
2018 - 2023
AHA Tobacco Regulation and Addiction Center (A-TRAC) 2.0
FDA / NHLBI U54
2013 - 2018
American Heart Association Tobacco Regulation and Addiction Center (A-TRAC)
NHLBI P50 HL120163-01 TCORS
2002 - 2014
Mapping Susceptibility Loci for Nicotine Dependence
NIDA DA-12844
2010 - 2011
A Second Phase 3, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study to Assess Efficacy, Immunogenicity and Safety of 3'-aminomethylnicotine-P. aeruginosa r-Exoprotein A Conjugate Vaccine (NicVAX) as an Aid to Smoking Cessation
Nabi Biopharmaceuticals
2008 - 2010
Influence of Provider Individual Differences on Tobacco Treatment Training Outcomes
Pfizer
2005 - 2009
Tobacco Cessation via Public Health Dental Clinics
NCI R01 CA107442-01A2
2003 - 2007
Tobacco Quitlines: Adjunct to Dental Interventions
NIDA DA-017972-01
2004 - 2005
Clinical Trial DRI5154
Sanofi - Synthelabo
Comparison of the Efficacy and Safety of 3 Oral Doses of SSR591813L, 20 mg, 40 mg, 80 mg twice daily versus Placebo, as an Aid to Smoking Cessation. A US, Multi-Center, Randomized, Double-blind, 4-Arm, Fixed Dose, 7-Week Treatment, PHASE II Trial.
2002 - 2005
Clinical Trial EFC4796
Sanofi - Synthelabo
Comparison of the Efficacy and Safety of 2 Oral Doses of Rimonabant, 5 mg / day or 20 mg / day, versus Placebo, as an Aid to Maintenance of Smoking Cessation - A Multiple Country, Randomized, Double-blind, 5 Arm, Placebo-Controlled, Parallel-Group, Fixed Dose, 2-year, Multi-Center, Phase III Trial: 1-Year Treatment, 1-Year Follow-up.
2002 - 2005
Smoking Cessation Research in Primary Care Treatment Centers
GlaxoSmithKline
2002 - 2003
Clinical Trial A3051018
Pfizer
A Forty-Week, Double-Blind, Multicenter, Non-Treatment Study Extension to Study A3051007 Evaluating the Efficacy of Four Dosing Strategies for CP-526,555 (0.5 mg BID, titrated 0.5 mg BID, 1 mg BID and titrated 1 mg BID) in Smoking Cessation.
2001 - 2003
Chewer's Choice
NCI
2001 - 2002
Clinical Trial A3051007
Pfizer
A Twelve-Week, Double-Blind, Placebo-Controlled, Randomized, Multicenter Study Evaluating the Safety and Efficacy of Four Dosing Strategies for CP-526,555 (0.5 mg BID, titrated 0.5 mg BID, 1 mg BID and titrated 1 mg BID) in Smoking Cessation.
1999 - 2002
Guideline Implementation for Tobacco Study
Veterans Affairs HSR&D